THORNE - Basic B-Complex - Tissue-Ready Vitamin B Complex Supplement with Choline - Supports Cellular Energy Production, Brain Health & Red Blood Cell Formation* - Gluten-Free - 60 Servings

Updated as of 10/10/2022: I have known that I have the MTHFR gene mutation for about 12 years now. Even after diagnosis, I was using a few other B-complexes which I though were o.k. for my condition, but I did not realize that the B6 was not methylated. Turns out B6 has to be in the form of Pyridoxal 5-Phosphate, NOT Pyroxidine, to be more bioavailable to those who have MTHFR and do not methylate properly. I never knew that until about 5 years ago; the doctor I tested with didn't explain that part. After this discovery, I researched various B-complex formulas, and picked this one. I also wanted a B-complex that had methylated folic acid and that did not have a super high dose of methylcobalamin (B12), since my blood was testing high for B12 already. This formula fit the bill very well. A few other tips: 1) The amount of methylated folic acid per capsule here is low (400mcg). If you only take one capsule per day, I would also recommend taking additional methyl-folate if you do not methylate. However, please first discuss with your chosen physician, if possible. 2) If you take B6 in its methylated form of Pyridoxal 5-Phosphate (a.k.a. P5P), you also need to take magnesium so that the P5P pathway will work properly. .Without at least some magnesium to work with, you may end up feeling tired and with lower energy, which is probably not what you want. 3) B6 - along with certain co-factors like magnesium, zinc, vitamin-C, and folate, is necessary for the production of certain neurotransmitters like GABA and norepinephrine, as well as for the conversion of tryptophan or 5-HTP into serotonin. So you may want to consider taking some of these additional co-factors to enhance your results with this product (only folate is included in this product, you would have to buy the rest separately). Also note: Tyrosine is also required for the synthesis of dopamine, but I have not tried taking that yet. I believe I have been low in neurotransmitter production, and my nervous system has been a mess, due to a 12-year highly stressful job and the resulting sky-high cortisol levels (Thankfully, I am no longer at that job!). It's been getting better slowly now.....it takes time and it's also very helpful to decrease your sugar and simple carb intake (e.g. white flour). 4) B6 and zinc are both needed for the production of pancreatic enzymes and hydrochloric acid, so if you have low stomach acid / poor digestion, this may help. (Zinc is not included in this formula but you may wish to add it if you are looking to help your production of digestive enzymes) In summary, this formula really helps with all the above, and it may help you too. Douglas Labs also makes a similar formula although it has some variation in it's mix. Best wishes to you. Addendum, additional updates since 2017: I had started taking this Thorne Basic B once a day plus an additional 50mg -100mg of P5P back in 2017-2018. Sometimes I would miss a day of both, I'm not perfect :). Eventually I got more disciplined and was taking the Basic B twice a day. I felt that was working better for me. Overall I can say for sure that the combo has helped to calm down my nervous system. I even went through some serious surgeries and medical procedures (extremely stressful) in 2017 and 2018, and in the past I would be a nervous wreck 24/7 and would not be able to calm down. However, I no longer get that uncontrollable anxiety anymore, although there can be some days where I can still fall into a depressive state. Magnesium powder or capsules have also helped keep me calmer (at bedtime), and I have taken some Skullcap, Ashwagandha, and/or Passionflower at times to further calm myself down as needed. Since 2018 I have also tried other methylated B-complex formulas like MethylPro, Douglas Labs, Pure Encapsulations, Nordic Naturals, and Metabolic Maintenance - just to experiment. However I keep returning to this one because it seems to work the best for my physiology. Together with the P5P, this has been like a lifeline for me. I hope it can work for you too if you decide to try it.

These B-complex vitamins are easy to take and make a noticeable difference in energy levels. High quality, effective, and convenient.

Excellent quality. No substantial odors or offputting taste. I take it in the morning on a mostly empty stomach or just after having some black tea and so far no issues and no bad side effects. The capsule is fairly large but I prefer taking a single large capsule like this one over taking two capsules, as I've had to do for other supplements. I noticed positive improvements in my mood after taking one pill daily for about two weeks. Would recommend.

I had a B deficiency on one round of labs, and we determined the supplement I had been taking just wasn’t cutting it. These vitamins seem to absorb much better, and also have the FULL B complex, not just certain ones. Not only are my levels back up, but they are high enough that I’m having to take this supplement less frequently. Thorne makes good and reliable products, from my experience.

Good quality

I really like this Thorne Basic B Complex as a straightforward daily B supplement. I personally take it to support overall energy, stress resilience and a healthy nervous system, and I do feel generally better and more “even” on days I take it. It also seems to help my nail strength over time. The formula uses active forms like methylfolate and methylcobalamin, which I look for, and the ingredient list is clean with no sugar or unnecessary fillers. The capsule is a manageable size and easy to swallow, with no real taste or aftertaste. For the quality of the forms and doses you get, I think it’s good value for money, and overall it feels like a solid, well-formulated B complex from a brand I trust.

I had been taking a B Complex supplement made by a known and popular brand. Question: You know when you take a supplement-yet are unsure of it's effects or help your body? That's where I was. A friend recommended Thorne Pharmaceuticals; especially this B Complex. I ordered this and began taking it. My mood has been more even- (I have anxiety and depression.). Another reason for this supplement was experiencing severe craniofacial hyperhydrosis for many years. I looked into potential causes for this condition and found that B12 and/or Folate deficiency could be the culprit. After taking this for 3 days, I experienced something I hadn't for years. My body felt cool. I actually felt cold later that night! I did not realize how poorly my body's temperature regulation had become. I am not getting drenched in awful sweats on a daily basis, as had become my norm. This has been a HUGE help in my life. I can wear make-up again without becoming drenched in eccrine perspiration. My hair would look like I had just run water over it. I could squeeze my hair and have water literally running through my fingers. Embarrassing to say the least; life altering in the negative-absolutely. Not any more. Hyperhydrosis can come from various etiologies- Primary & Secondary. Dermatologists use Botox treatments or prescribe Anti-Cholinergics to treat as I have read. I see my M.D. next week to discuss this, and ask to get Lab work done. I do not know that I have deficiencies, however it seems this may have been the case! Nothing happened with another Brand's B Vits. Read Thorne's label(s). Yes it's more costly than others but it works, and you can feel the difference. I also began supplementing with high dose Vit D3, and take Magnesium Citrate. Remember that D3 needs a fat to work properly, so take with avocado, or your morning meal? (I am 65, female and do not eat much meat.). Hope this might help someone.

Good quality

Benefícios reais.

Melhor suplemento de vitamina B para as minhas necessidades

The smell is like maggis chicken

某巨大掲示板で見かけたので興味本位で購入いたしました。効果あります！身体が軽く疲れにくくなって驚きました♡ あと、化粧ノリ抜群です！！！

Producto increible!