How would i connect my guitar to this?

Input 2 has a switch that allows for High-Z input, such as a guitar. There is no need for a DI box.

Does this hardware come bundled with the Cubase Software?

A software key is provided in the package for Cubase AI. You will have to register the product, create a Steinberg account and enter your software key to get access to Cubase AI download. The file is about 16gb, if I recall correctly, and download is not possible without signing up for the Steinberg account.

Does having a loopback function eliminate the need for a device like the Irig Stream?

May depend on what you are trying to do, but the loopback function will allow you to stream your input and DAW together.

Is the 5 dc volt power adapter included

No. It is assumed you will power it via the computer you connect it to.

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Steinberg UR22C 2x2 USB 3.0 Audio Interface with Cubase AI and Cubasis LE

Product ID: 220471979

Details

Brand
Steinberg
Compatible devices
Laptop
Connectivity technology
USB
Number of channels
2
Supported software
Cubase AI & LE

⚡USB 3.0 super speed

🎙️32-bit/192kHz converters

🎛️Zero-latency DSP effects

Description

🎧 Elevate your sound game—pro studio quality in your backpack!

VERSATILE I O FOR EVERY SETUP - Plug in microphones, guitars, and MIDI gear with dual D-PRE preamps and onboard MIDI I/O.
STUDIO QUALITY SOUND ANYWHERE - Capture pristine 32-bit/192kHz audio with industry-leading converters for professional-grade recordings.
LIGHTNING FAST USB 3 0 CONNECTIVITY - Experience seamless, lag-free data transfer and power delivery via USB-C for ultimate mobile production.
ZERO LATENCY MONITORING WITH EFFECTS - Mix and monitor your tracks live using DSP-powered effects without any delay—perfect for flawless performances.
PLUG PLAY WITH CUBASE AI CUBASIS LE - Jumpstart your creativity with included DAW software optimized for Windows, Mac, and iPad workflows.

The Steinberg UR22C is a compact, rugged 2x2 USB 3.0 audio interface delivering ultra-high resolution 32-bit/192kHz recording. Featuring dual D-PRE preamps, onboard DSP effects for zero-latency monitoring, and versatile connectivity including MIDI I/O, it’s designed for seamless mobile music production on Windows, Mac, and iPad with included Cubase AI and Cubasis LE software.

Specifications

ASIN	B07YFH671V
Audio Input	USB
Best Sellers Rank	97,912 in Musical Instruments & DJ ( See Top 100 in Musical Instruments & DJ ) 419 in Computer Audio Interfaces
Brand Name	Steinberg
Compatible Devices	Laptop, Personal Computer
Connectivity Technology	USB
Customer Reviews	4.4 4.4 out of 5 stars (489)
Frequency Response	192000 Hz
Global Trade Identification Number	00889025119658
Item Dimensions D x W x H	20.5D x 23.4W x 10.5H centimetres
Item Type Name	Audio Interface
Item Weight	1 Kilograms
Manufacturer	Steinberg
Manufacturer Part Number	UR22C
Maximum Sample Rate	192 KHz
Model Number	UR22C
Number of Channels	2
Number of Items	1
Operating System	Windows
Supported Software	Cubase AI & Cubasis LE
UPC	889025119658
Unit Count	1.0 count

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