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🛡️ Protect your pup like a pro — because your dog deserves the best defense!
FRONTLINE Plus Flea and Tick Treatment for Medium Dogs (23-44 lbs) offers a fast-acting, waterproof topical solution that kills fleas, flea eggs, larvae, chewing lice, and ticks for 30 days. Trusted by pet owners for over 20 years, it uses fipronil and (S)-methoprene to break the flea life cycle and provides continuous protection even if your dog gets wet. Easy to apply monthly, it’s designed for dogs as young as 8 weeks and ensures comprehensive pest control with just one dose.

















| ASIN | B0002J1FN0 |
| ASIN | B0002J1FN0 |
| Active Ingredients | fipronil and (S)-methoprene |
| Age Range Description | All Life Stages |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #421 in Pet Supplies ( See Top 100 in Pet Supplies ) #6 in Dog Flea Drops |
| Brand Name | Frontline |
| Customer Reviews | 4.4 4.4 out of 5 stars (23,904) |
| Date First Available | October 2, 2001 |
| Department | Pet Supplies |
| Dog Breed Size | Medium |
| Included Components | 3 doses |
| Is Discontinued By Manufacturer | No |
| Item Form | Liquid |
| Item Type Name | Flea and Tick Treatment for Dogs Medium Dogs |
| Item Weight | 1 Ounces |
| Item model number | P004FLTSP-23-44 |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer Part Number | P004FLTSP-23-44 |
| Manufacturer recommended age | 1 month and up |
| Model Number | P004FLTSP-23-44 |
| Product Dimensions | 5.75 x 0.75 x 4.5 inches; 1 ounces |
| Scent Name | Unscented |
| Target Species | Medium Dog, 23-44 Pounds |
| UPC | 816306017808 717077000641 742583966532 788995790150 793591599939 891962001071 350604401315 705105831718 643996060353 350604287100 611102267675 078997022220 010756261372 |
| Unit Count | 3 Count |
| Volume | 0.14 Fluid Ounces |
| Warranty Description | If you are not satisfied with FRONTLINE Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842 |
M**N
Dog Flea and tick - good quality
So far so good.
B**A
Excellent product, BUT...
This is an excleent product, but it is not a miracle worker. In other words, you need to use the stuff properly. (1) this product is water resistant...not soap resistant. So if you use this stuff then go and use some of that heavily perfumes soapy shampoo that msot people use..then you are washign it right off. (2) if you chose to bathe your dog..bathe him/her first then wait 2-3 days THEN apply the product so that it will be distrubited properly. (3) Remember that if you have a heavy flea problem that you need to treat the pet and the environment. You can't jsut put it on the dog and not get rid of the fleas in your house, car, yard, etc.. Yeah it will kill the fleas on him/her, but they will get reinfested with fleas everytime they go back into the flea filled environment. This is the only product that I use for my dog. Of you purchase ANYTHING over the counter (biospot, hartz ::shudders::, etc) then you are wasting your money. Flea dips work, but they only kill the fleas that are on the dog when you bathe him/her. Frontline PLUS is great becasue it keeps killing for up to a month. Also, Frontline Plus has a better range of killing fleas than plain ole' Frontline. The "PLUS" means that it kills larvae and eggs and so much more than adult fleas. IF USED CORRECTLY and ROUTINELY this is an EXCELLENT product!!! I highly recommend it. This product also kills ticks.
D**Z
Frontline is perfect for monthly maintenance!
Use this once a month for my dog. It does exactly what it's supposed to. Just make sure you read the directions to make sure you're getting the right size for your pet. Super easy to open. My papa has had no skin irritation, or discomfort after I apply it. Definitely a must to avoid any type of flea or tick infestation
A**.
Trusted protection, but effectiveness can vary by region
This is a well-known and trusted flea & tick treatment that’s easy to use and works as part of a monthly routine. Each application provides about 30 days of protection, and the formula is designed to kill adult fleas, eggs, larvae, ticks, and even chewing lice. Application is simple—just apply it to the back of your dog’s neck, and it spreads through the oils in the skin for full-body protection. It’s also waterproof after drying, which is helpful for active dogs. In terms of performance, it works well for many dogs and can kill adult fleas within about 12 hours and ticks within 48 hours, helping break the flea life cycle. On the downside, effectiveness can vary depending on your area—some users report it’s not as strong as it used to be, especially in high-flea regions. It can also take a full day or so to start working, and you’ll need to stay consistent with monthly use.
B**T
Gets rid of pests
FRONTLINE Plus has been very effective at keeping fleas and ticks under control. It’s easy to apply, doesn’t have a strong odor, and hasn’t caused any irritation. I like that it provides long lasting protection with just one monthly dose. This has been a reliable product for us and definitely worth the purchase. Your pets will be happy you bought it.
J**E
Nice working product
Easy to use, great price,h my dog will not take $80 tablet for 3 months. Works better.
T**Z
Doesn’t work in March in San Antonio TX at all!!
Not working so well. Have been using on the absolute reg and dog still getting ticks. They don’t die either!! She also gets the oral stuff regularly and I spray the yard! What the heck!! I also spray her bedding etc w the natural stuff and her as well. Really the natural spray is the only decent stuff but can’t spray her constantly. Do spray bedding twice a day. Any suggestions will be appreciated. No one wants to see a pic of ticks. 😬😵💫
J**N
good
don't know yet
D**L
It says 6-doses but what arrived was only the 3-dose pack.
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