Do comfortzone refill fit in the feliway difusers?

90% Sure yes. I've been using Comfort Zone & Feliway interchangeably, just what I can get ahold of, and haven't had a diffuser fit problem.

Does the 2x refill work with the original diffuser, I see the outer casing is different, is that needed for the 2x to be effective?

Yes, they are backward compatible.

Do all contain a diffuser?

No, there is no diffuser in this pack. You will see a picture of the diffuser on the front of the package of those that contain a diffuser(s).

How well does it work for indoor cats marking because outdoor strays are driving them crazy?

I've not used these specifically in that situation, though I know exactly how aggravating that is! I've introduced several rescued feral cats into my main group of indoor cats in years past, and only wish I would have had this product back then. I can't say it will fix the problem you're having, but if it were me, I would sure TRY it. I'd saturate the home with the plug-in diffusers, then spray directly on whatever areas your cats are in when they see/hear the outdoor cats. I honestly think it would be worth a try. Right now I have an outdoor kitty who comes and lies up against the door here (I take care of her, feed her, and she has shelter and a heated bed!), but my indoor cats here just lie against the door on the INSIDE when they hear her. No meowing, no crying, no scratching. I'm in a small apartment and two plug-in diffusers seem to work wonders. I personally hope to never be without this product... even my petsitters always remark on how they "can't believe how well everyone in here gets along". Good luck.

Comfort Zone Multicat Refills

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