

🐾 Stay ahead of fleas with Advantage XD — because your cat deserves long-lasting, hassle-free protection!
Advantage XD Large Cat Flea Prevention offers 8 months of powerful flea control with 4 topical doses, each providing 2 months of fast-acting, contact-killing protection. Featuring a fragrance-free, naturally derived Spinetoram formula recognized by the US EPA Green Chemistry Challenge, it’s easy to apply and effective for cats over 9 lbs, indoors or outdoors—no prescription required.













| Active Ingredients | Spinetoram |
| Brand | Advantage |
| Customer Reviews | 4.3 out of 5 stars 2,738 Reviews |
| Item Form | Topical |
| Item Volume | 8 Milliliters |
| Item Weight | 1.12 ounces |
| Scent | Unscented |
C**W
Good
I use this on one of the large neighborhood cats to help with his fleas. It seems to work really well for him. He is always highly insulted when I put it on, but in the end, it really helps his comfort level.
A**R
Excellent Choice for My Cat
Works very well on My Cat! Great Price
M**R
Worked for us
This worked well for both of my larger cats. Haven’t seen any fleas since. Will purchase again. Does have a slight odor but goes away fairly quickly
R**N
Flea's
It worked right away, about 2 hours. The trouble I had was with the packaging and the little dropper. The small application dropper was hard to squeeze; when you did, you really didn't know if it got to the cat's neck. Other than that I would buy again.
R**D
Rid fleas instantly
My indoor-only cats were previously on frontline and still got infested with fleas. As soon as I switched them to Advantage the fleas were all gone practically overnight. This product saved them (and me) from insanity.
C**N
Advantage xo for cats over 9 lbs.
Caution!!! Don’t buy this product!!!!! We usually get a subscription from the vet during flea season, just in case. Our indoor cat hasn’t really needed it, up until now. Mochi somehow got fleas?!!! Unfortunately the subscription ihss expired. Mochi would scratch every once in a while, but we noticed it was a bit more than a usual itch or scratch to get to certain spot. So, we decided we will get an Advantage brand flea treatment (non/prescript) because we had pre-used a(different type) Advantage in the past and it worked pretty good,and it’s better to use it than nothing at all at least until we can go to vet. We purchased Advantage XO which was an advanced/improved version of previous product I had bought but, with an treatment extended for 2 months use in just in one dose.. save money sounds great,, and after reading reviews the customers had claimed that this product worked well. So we ordered it. We applied Advantage XO to our cat- hoping he will have some relief, and control the fleas. In just minutes after applying on the back of our cats neck, he started itching & scratching even more. he would walk and suddenly he was falling/ plopping himself down quickly on floor in order to scratch/bite where the fleas were. He was making a noise as if sucking/chewing on his skin to be rid of his discomfort. I have never heard him do that and made me keep an eye on him. It made me feel a bit worried. We had thought okay the fleas must be scattering/freaking out- so it must be working. My cat had a hard time that night scratching more than ever. I felt sorry for him.The next day it seemed like maybe it was slowing down he wasn’t scratching like previous day. I thought wrong he started scratching not as crazy but consistent. In the end it seemed to make the fleas worse if possible I don’t know?! But I do know I will never buy this again. I don’t want my cat to suffer or see what I did as a reaction to this flea treatment. I wasted my money, and in the end, I didn’t help him to feel better. Decided to go to the vet, much safer.
J**A
Seriously, this stuff works.
Oh my gosh, let me just say that this medicine works wonders. I was using the same brand but the month-to-month, but my cat is huge so it stopped working for him. I ordered this stuff and gave it to him in the very next day. I could tell such a difference. And it's been only 3 days and he is so happy. He's not scratching like he was. I think that this was the best medicine for my cat. Everybody's cats are different but for my cat, plain white 18 pounder male indoor cat. Worked amazing. I'd recommend this medicine to anybody that is having problems getting rid of fleas on their cats or ticks or ear mites. Works wonders quickly.
N**L
Works great at killing and preventing flees!
I Had tried all the flee meds offered at petco locally but none of them worked to control my outdoor cats flees. I did some research and found out flees in my area are becoming immune to most flee medications they simply wont work at kills flees or eggs. I asked vet friend and he recommend this medication as he hasn't seen the local flee population build immunity to it. I ordered some in the spring and it worked great! Kept flee populations near zero and rest was easly removed with a flee comb. I recommend this product as prevention AND treatment for flees.
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