--- product_id: 18122351 title: "maxxipaws maxxiSAMe SAM-e for Dogs, Liver & Cognitive Support Powder 5.3 oz" brand: "maxxipaws" price: "KD 31.86" currency: KWD in_stock: true reviews_count: 13 category: "Maxxipaws" url: https://www.desertcart.com.kw/products/18122351-maxxipaws-maxxisame-sam-e-for-dogs-liver-and-cognitive-support store_origin: KW region: Kuwait --- # B Vitamins & choline enhance metabolism Artichoke stimulates bile production SAM-e boosts liver & brain health maxxipaws maxxiSAMe SAM-e for Dogs, Liver & Cognitive Support Powder 5.3 oz **Brand:** maxxipaws **Price:** KD 31.86 **Availability:** βœ… In Stock ## Summary > 🐾 Elevate your dog’s golden years with brain & liver brilliance! ## Quick Answers - **What is this?** maxxipaws maxxiSAMe SAM-e for Dogs, Liver & Cognitive Support Powder 5.3 oz by maxxipaws - **How much does it cost?** KD 31.86 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.com.kw](https://www.desertcart.com.kw/products/18122351-maxxipaws-maxxisame-sam-e-for-dogs-liver-and-cognitive-support) ## Best For - maxxipaws enthusiasts ## Why This Product - Trusted maxxipaws brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - β€’ **Effortless Daily Dose:** Powder form mixes seamlessly with foodβ€”no pills, no hassle, just pure wellness. - β€’ **Mood & Mobility Boost:** Supports dopamine function and joint health to keep your dog alert and active. - β€’ **Natural & Trustworthy:** Non-GMO, no artificial additives, proudly made in the USA for discerning pet parents. - β€’ **All-Breed, All-Age Formula:** Tailored for every dog, from playful pups to wise seniors, ensuring lifelong vitality. - β€’ **Liver & Cognitive Powerhouse:** Clinically-backed SAM-e supports liver regeneration and sharpens canine cognition. ## Overview maxxipaws maxxiSAMe is a premium 5.3 oz powder supplement designed to support liver health and cognitive function in dogs of all breeds and ages. Featuring clinically recognized SAM-e combined with artichoke, B vitamins, choline, and inositol, it promotes hepatic regeneration, healthy dopamine activity, and mental alertness. Its easy-to-mix powder form allows convenient daily dosing with food, eliminating the need for pills or fasting. Trusted by thousands of pet owners, maxxiSAMe helps slow cognitive decline, supports joint health, and enhances mood, making it an essential addition to senior dog care routines. ## Description desertcart.com : maxxipaws maxxiSAMe SAM-e for Dogs, Liver & Cognitive Support Powder 5.3 oz | Promotes hepatic function, mental sharpness, mood, energy & healthy ageing with SAMe, artichoke & B vitamins : Pet Supplies Review: doge says: much yuck. do not want. (at first... then do want!) (with updates!) - Update 10/15/2025: Hi there, me again. Now that it is 8 years later, Barney's adopted little brother Maximus is well into his senior years. He's in great shape for his age, which we estimate to be around 13 years (he's a rescue pittie), but he's started showing some signs of cognitive decline - restlessness, pacing, and panting, especially at night. We are managing his relatively mild arthritis stiffness with meds from our vet, thinking that's why he was so agitated, but the cognitive symptoms persisted. That's when I remembered how much this supplement helped our Barney all those years ago. We've been loyal to the Maxxi brand this whole time - Max gets the Omega oil and MaxxiDigest on his food daily to help with his coat and tummy (ya boy gets some serious diarrhea and gas that'll knock you out without it) - so I can't believe it took me this long to remember that MaxxiSAMe exists. Unlike Barney, Max gobbles this stuff right up with his food, no weird cheese sushi roll required. Thank you, MaxxiPaws, for continuing to put out a quality product. ---- Final Barney update 5/24/2017: This will be my final update to this review, as we unfortunately had to say goodbye to our wonderful dog Barney last week after his slow onset of degenerative myleopathy had progressed too far. I cannot say enough good things about the MaxxiDog company as they helped us find solutions to make Barney's last year+ as comfortable and happy as it could be. I truly believe that the MaxxiSAMe product had a positive effect for Barney and was key in making his last time with us a happy one, as it really seemed to help mitigate his symptoms of Canine Cognitive Dysfunction (CCD). I have changed my review to five stars to reflect this. Please continue reading below for the original review, and the other updates on how we ended up using the product. (Spoiler: The most effective way to get Barney to eat it was to do two small pumps of MaxxiOmega oil with it to make a paste, and then put the paste in American cheese like a weird little sushi roll! He never turned his nose up at this option.) Thank you again to the MaxxiDog company for your excellent product and wonderful customer service. ---- (Original review:) My dog Barney is well into his golden years and has is showing some pretty strong signs of canine cognitive dysfunction (CCD; basically, doggie dementia) such as night waking/panting, getting lost or stuck in corners, licking, digging at the floor, and fecal incontinence. So, I powered up the ol' computer and did some research. It turns out there isn't a ton you can do for it once they've got it, but there are supplements that can help manage some of the symptoms and keep it from progressing as quickly. Enter: SAMe and choline. These two seemed to pop up the most in my searches but my head was spinning about what product to buy. Well, this MaxxiSAMe stuff handily has both! Awesome! Now, a little bit about Barney - Barney has been anywhere from 77 to 90 pounds since I've known him. This dog LOVES to eat. He's not picky, either - he eats 'yard treats' (if you catch my drift) regularly, for goodness sake. He once ate a raw zucchini off the floor (and immediately threw it up, but that's beside the point). Now that we've been more careful about his portion sizes he acts like we're starving him to death (I assure you, we are not) and scavenges even more. But as soon as I put this stuff on his food, Barney went on a hunger strike. He will NOT touch the stuff. It's crazy. I even tried burying cheese in his bowl thinking he'd at least eat his way down to the cheese - NOPE. Not interested. I really wish this came in pill form. I've resorted to trying to squish the dosage up in cheese and give it to him that way, which is pretty difficult since he is on the highest dosage (1 tsp per dosage, twice a day), and the supplement needs to be inside the cheese for him to eat it. I have made some messes. I think my next attempt may involve deli meat since that won't fall apart like cheese slices... though now I have visions of Barney biting into the powder ball in the meat and causing an explosion. He's only had his full dosage(ish... the part that hasn't scattered out of the cheese all over the floor anyway) for a day or two. If I notice some improvement or come up with a better method of administration, I'll absolutely come back and edit my review. I really, really want to love this product. But for now, I give it 5 stars in theory and Barney gives it a 1 star in taste so we'll compromise and call it a 3. ---- UPDATE 4/28/2016: We went through two jars of this stuff, and multiple administration methods (since adding it straight to dry food was NOT an option). First I'll talk about the effects it has had on him, and then I will talk about how we've been giving it to him. EFFECTS: After giving him two jars of this, I didn't buy a third. After a few days of not being on it, his CCD symptoms increased fairly dramatically - walking around panting/whining at night, getting lost in corners, pooing inside, etc. He was still doing some of those things SOMETIMES, so it's possible that the timing of his symptoms was coincidental with stopping the MaxxiSAMe. However, I had forgotten just how bad his symptoms used to be, especially the night symptoms - we were all sleeping very terribly for a few days there. So I bought another jar hoping it would help him, and I think it has. We all slept through the night better the last couple of nights, anyway! This is why I've upped my rating to 4 stars (was previously 3). ADMINISTRATION: Oh boy. Well, the folks at MaxxiSAMe were kind enough to respond to my review in both email form and comment form (below) and include some ideas for getting him to take it, which is super awesome of them. Here is what we've tried, and what has and hasn't worked - 1. Paste method: Add a small amount of water to make a thick paste. Give to dog like treat. This worked for maybe a couple of weeks, and now he just turns his nose away from it when I try to give it to him this way. The MaxxiSAMe folks also suggested mixing it with something he likes, but I don't think this would work, for reasons I'll get to in a moment. 2. Soft food method: Barney was on meds that made his stomach upset for a while, so to get him to eat, I would add warm water to his dry kibble food to make it soft and appealing. I could add the MaxxiSAMe directly to the soft food and he'd eat it right up. *shrug* 3. Paste + cheese method: This is what we're doing now. I add a VERY small amount of water to make a thick paste, which I form into a ball with my fingers. Then I smash cheese around it so that none (or at least very little) of the MaxxiSAMe ball is showing. If it is showing, he will not touch the stuff - or sometimes will sort of "work" at it to get the cheese off and spit the MaxxiSAMe out. This is why I don't think it would work to mix the paste with something he enjoys: he would still know the MaxxiSAMe is in there. I think this method would work better with lunch meat, but that's not something we normally have around the house, and it goes bad faster than cheese slices. This method would probably work okay with a PillPocket type treat that has a large enough pocket. So, in conclusion, Barney still thinks the stuff is super gross which makes administration a bit of an ordeal, but I have reason to believe it might be helping his CCD so that outweighs any difficulties in giving it to him. I do still wish it came in tablet form; I picture it being like Cosequin, where it's not a coated tablet but more of a compressed powder type tablet that can be broken if needed. Thanks again to the makers of this product for supplying such a high quality product, and for responding to reviews in such a thoughtful, detailed way! ---- UPDATE 6/17/2016: After my last update, the owners of MaxxiSAMe were not content that Barney still wasn't super into the stuff. They actually sent me a free bottle of their MaxxiOmega oil to try mixing that with the MaxxiSAMe, which is super awesome of them. Turns out, it totally worked. I mix his SAMe dosage with about a pump and a half of the oil, smear it on a piece of cheese and wrap the cheese sushi-style, and he gobbles it right up. He still won't QUITE eat it without cheese (though he acts like he MIGHT when I've offered it to him), but I at least don't have to try to smash the cheese all around it to hide every speck of the MaxxiSAMe. Thank you!! Review: The SAMe is helping and the cognitive benefit is huge (update) - I previously gave our 10-yr old pointer a chewable SAMe tablet to help control unexplained elevated liver values, but manufacturer changed the formula and our dog would no longer eat it unless buried in food. Since it needed to be given on an empty stomach, that was not ideal. I regularly search for any alternative products--finding nothing much different--and suddenly there was MaxxiSAMe claiming to be fine given with food. Information on the product said it was beneficial for liver health as well as cognitive function. I wasn't looking for the latter, but didn't think it would be in any way a harmful effect. After a brief period of slowly introducing this powder--she didn't care for the flavor, due I assume to the heavy artichoke taste--she began happily eating her food with this supplement in it. It was helpful that she gets some wet food; when it was just dry food the powder would fall to the bottom more readily and got left there. After several weeks we were surprised to notice that she was reverting to more energetic, alert, puppy-like behaviors, and since nothing else had changed we attribute this to improved cognitive function from MaxxiSAMe. I have recommended MaxxiSAMe to my veterinarian who agreed it looks great and seems worthy of trial by other patients. I gave it only 4 stars because the taste was a hurdle for our dog to get over. Also--although I have no reason to blame this product--her liver values have increased a bit, which is not uncommon for her from time to time anyway; but I give her SAMe to manage them so time will tell how they might fluctuate as she stays on this product. As long as they don't spiral out of control, the SAMe is helping, and the cognitive benefit is huge. UPDATE 11/26/17 -- Recently my pointer had her liver values checked again and they were much lower than before! That was the only hold-up in giving this product five stars, so now I can do that and confirm that this product has been great. I have come to trust this company and also have started my dog on their MaxxiFlex joint supplement to help with her arthritis and this is helping her too. ## Features - LIVER HEALTH CARE: A supplement for any pet dog with liver issues. Our key ingredient SAM-e, can aid the hepatic (liver) function, support cell regeneration & safeguard against further damage. - AID COGNITIVE FUNCTION: maxxiSAMe acts as a brain function stimulant containing SAM-e, which can support the dopamine function in the brain, to assist cognitive performance. - ADDITIONAL NATURAL INGREDIENTS: Artichoke can help to stimulate the production of bile in the liver. B Vitamins aid liver metabolic function & are recommended for liver problems. Choline & Inositol assist in removing liver fatty deposits. - SUPPORT FOR ALL DOGS: Suitable for any canine breed. May help slow mental decline & aid alertness in senior or older dogs; plus supports joint health & promotes positive mood. - GIVEN WITH FOOD: Unlike inconvenient tablets, our natural flavor powder supplement is given easily with food, for quick absorption; add 1 scoop to food daily per 30lb of weight. Suitable for small, medium & large dogs. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00ZD4IOV0 | | Additional Features | Cognitive Support (second use), Made in USA, No Artificial Additives, Non-GMO | | Age Range (Description) | All Life Stages | | Age Range Description | All Life Stages | | Animal Food Diet Type | Veterinary Diet | | Best Sellers Rank | #56,012 in Pet Supplies ( See Top 100 in Pet Supplies ) #40 in Dog Antioxidant Supplements | | Brand | maxxipaws | | Brand Name | maxxipaws | | Breed Recommendation | All dog breeds | | Customer Reviews | 4.5 out of 5 stars 916 Reviews | | Dog Breed Size | Medium | | Flavor | Natural | | Included Components | 5.3 oz tub of maxxiSAMe powder, Measuring scoop | | Item Form | Powder | | Item Weight | 204 g | | Manufacturer | maxxipaws | | Manufacturer Part Number | MD-MS100 | | Model Number | MSA-2015 | | Number of Items | 1 | | Occasion | Birthday | | Package Size Name | 5.3 oz (150 g) | | Pet Type | Dog | | Product Benefits | Complete formula with SAM-e, artichoke, B vitamins, choline and inositol, Easy to mix with food, no empty stomach needed, Supports everyday liver wellbeing, Supports healthy cognitive function in senior dogs, Supports healthy dopamine activity and alertness | | Special Ingredients | Vitamin C, Vitamin E | | Specific Uses For Product | Liver Care | | Target Species | Dog | | Unit Count | 5.3 Ounce | ## Product Details - **Age Range (Description):** All Life Stages - **Brand:** maxxipaws - **Flavor:** Natural - **Item Form:** Powder - **Specific Uses For Product:** Liver Care ## Images ![maxxipaws maxxiSAMe SAM-e for Dogs, Liver & Cognitive Support Powder 5.3 oz - Image 1](https://m.media-amazon.com/images/I/71ruGsAQYWL.jpg) ![maxxipaws maxxiSAMe SAM-e for Dogs, Liver & Cognitive Support Powder 5.3 oz - Image 2](https://m.media-amazon.com/images/I/71z9R4PefKL.jpg) ![maxxipaws maxxiSAMe SAM-e for Dogs, Liver & Cognitive Support Powder 5.3 oz - Image 3](https://m.media-amazon.com/images/I/81+MVQq2J2L.jpg) ![maxxipaws maxxiSAMe SAM-e for Dogs, Liver & Cognitive Support Powder 5.3 oz - Image 4](https://m.media-amazon.com/images/I/71xxEuskVVL.jpg) ![maxxipaws maxxiSAMe SAM-e for Dogs, Liver & Cognitive Support Powder 5.3 oz - Image 5](https://m.media-amazon.com/images/I/81yt0OdDN6L.jpg) ## Questions & Answers **Q: How many scoops in a container?** A: Dear Samantha, Thank you very much for your interest in MaxxiSAMe which we really appreciate. There are 60 scoops of MaxxiSAMe in the container. The container contains 150 g of MaxxiSAMe and each scoop is 2.5g. The recommended maintenance dosage for a 30 lb pet is 1 scoop daily. We hope this helps but if there is anything else we can assist you with, please don’t hesitate to contact us directly. Kind regards, Alison Slater Customer Service Manager MaxxiDog **Q: Yes i have now moved to victoria bc, canada , and am told it will not ship here??? it is made in canada and i got it on amazon.com in san diego???** A: Dear JoanneThank you for your e-mail. We are very pleased that MaxxiSAMe has worked well for your pet.MaxxiSAMe is only available through us (MaxxiDog) and we currently only sell on Amazon in the USA, UK, Germany and France. Unfortunately Amazon.com does not ship to Canada. However, Canada and the European Union (EU) are "as we speak" in the process of signing free trade agreement which means you will be able to buy directly from any Amazon EU platform in the future. However, that does not resolve your current situation. We have e-mailed you personally with our recommendations and we will do everything we can to make sure your pet does not have to be without his MaxxiSAMe.Kind regards,Birgir and Asa GislasonOwners of MaxxiDog **Q: Can be or should be refrigerated? big difference.** A: Dear Gary,Thank you very much for your enquiry and your interest in MaxxiSAMe.MaxxiSAMe is recommended to be stored in a cool dry place and providing it can be stored in such conditions, it is not necessary to refrigerate.However, refrigerating once opened is the best way to guarantee that both these criteria are met. This is especially important in hot and humid climates when finding cool dry places can be challenging.We hope this addresses your question adequately but if you have any further queries, please don't hesitate to contact us directly.Kind regards,Alison SlaterCustomer Service ManagerMaxxiDog **Q: How many teaspoons are there in a scoop?** A: Dear Jan, Thank you very much for your interest in maxxiSAMe for dogs which we really appreciate. 1 scoop of maxxiSAMe for dogs equates to 1 level measuring teaspoon. 1 scoop of maxxiSAMe for dogs = 2.5 g and there are 60 scoops in the container (150 g). We hope this helps but if there is anything else we can assist you with, please don’t hesitate to contact us directly through your Amazon account. Kind regards, Alison Slater Customer Service Manager maxxipaws ## Customer Reviews ### ⭐⭐⭐⭐⭐ doge says: much yuck. do not want. (at first... then do want!) (with updates!) *by N***H on February 17, 2016* Update 10/15/2025: Hi there, me again. Now that it is 8 years later, Barney's adopted little brother Maximus is well into his senior years. He's in great shape for his age, which we estimate to be around 13 years (he's a rescue pittie), but he's started showing some signs of cognitive decline - restlessness, pacing, and panting, especially at night. We are managing his relatively mild arthritis stiffness with meds from our vet, thinking that's why he was so agitated, but the cognitive symptoms persisted. That's when I remembered how much this supplement helped our Barney all those years ago. We've been loyal to the Maxxi brand this whole time - Max gets the Omega oil and MaxxiDigest on his food daily to help with his coat and tummy (ya boy gets some serious diarrhea and gas that'll knock you out without it) - so I can't believe it took me this long to remember that MaxxiSAMe exists. Unlike Barney, Max gobbles this stuff right up with his food, no weird cheese sushi roll required. Thank you, MaxxiPaws, for continuing to put out a quality product. ---- Final Barney update 5/24/2017: This will be my final update to this review, as we unfortunately had to say goodbye to our wonderful dog Barney last week after his slow onset of degenerative myleopathy had progressed too far. I cannot say enough good things about the MaxxiDog company as they helped us find solutions to make Barney's last year+ as comfortable and happy as it could be. I truly believe that the MaxxiSAMe product had a positive effect for Barney and was key in making his last time with us a happy one, as it really seemed to help mitigate his symptoms of Canine Cognitive Dysfunction (CCD). I have changed my review to five stars to reflect this. Please continue reading below for the original review, and the other updates on how we ended up using the product. (Spoiler: The most effective way to get Barney to eat it was to do two small pumps of MaxxiOmega oil with it to make a paste, and then put the paste in American cheese like a weird little sushi roll! He never turned his nose up at this option.) Thank you again to the MaxxiDog company for your excellent product and wonderful customer service. ---- (Original review:) My dog Barney is well into his golden years and has is showing some pretty strong signs of canine cognitive dysfunction (CCD; basically, doggie dementia) such as night waking/panting, getting lost or stuck in corners, licking, digging at the floor, and fecal incontinence. So, I powered up the ol' computer and did some research. It turns out there isn't a ton you can do for it once they've got it, but there are supplements that can help manage some of the symptoms and keep it from progressing as quickly. Enter: SAMe and choline. These two seemed to pop up the most in my searches but my head was spinning about what product to buy. Well, this MaxxiSAMe stuff handily has both! Awesome! Now, a little bit about Barney - Barney has been anywhere from 77 to 90 pounds since I've known him. This dog LOVES to eat. He's not picky, either - he eats 'yard treats' (if you catch my drift) regularly, for goodness sake. He once ate a raw zucchini off the floor (and immediately threw it up, but that's beside the point). Now that we've been more careful about his portion sizes he acts like we're starving him to death (I assure you, we are not) and scavenges even more. But as soon as I put this stuff on his food, Barney went on a hunger strike. He will NOT touch the stuff. It's crazy. I even tried burying cheese in his bowl thinking he'd at least eat his way down to the cheese - NOPE. Not interested. I really wish this came in pill form. I've resorted to trying to squish the dosage up in cheese and give it to him that way, which is pretty difficult since he is on the highest dosage (1 tsp per dosage, twice a day), and the supplement needs to be inside the cheese for him to eat it. I have made some messes. I think my next attempt may involve deli meat since that won't fall apart like cheese slices... though now I have visions of Barney biting into the powder ball in the meat and causing an explosion. He's only had his full dosage(ish... the part that hasn't scattered out of the cheese all over the floor anyway) for a day or two. If I notice some improvement or come up with a better method of administration, I'll absolutely come back and edit my review. I really, really want to love this product. But for now, I give it 5 stars in theory and Barney gives it a 1 star in taste so we'll compromise and call it a 3. ---- UPDATE 4/28/2016: We went through two jars of this stuff, and multiple administration methods (since adding it straight to dry food was NOT an option). First I'll talk about the effects it has had on him, and then I will talk about how we've been giving it to him. EFFECTS: After giving him two jars of this, I didn't buy a third. After a few days of not being on it, his CCD symptoms increased fairly dramatically - walking around panting/whining at night, getting lost in corners, pooing inside, etc. He was still doing some of those things SOMETIMES, so it's possible that the timing of his symptoms was coincidental with stopping the MaxxiSAMe. However, I had forgotten just how bad his symptoms used to be, especially the night symptoms - we were all sleeping very terribly for a few days there. So I bought another jar hoping it would help him, and I think it has. We all slept through the night better the last couple of nights, anyway! This is why I've upped my rating to 4 stars (was previously 3). ADMINISTRATION: Oh boy. Well, the folks at MaxxiSAMe were kind enough to respond to my review in both email form and comment form (below) and include some ideas for getting him to take it, which is super awesome of them. Here is what we've tried, and what has and hasn't worked - 1. Paste method: Add a small amount of water to make a thick paste. Give to dog like treat. This worked for maybe a couple of weeks, and now he just turns his nose away from it when I try to give it to him this way. The MaxxiSAMe folks also suggested mixing it with something he likes, but I don't think this would work, for reasons I'll get to in a moment. 2. Soft food method: Barney was on meds that made his stomach upset for a while, so to get him to eat, I would add warm water to his dry kibble food to make it soft and appealing. I could add the MaxxiSAMe directly to the soft food and he'd eat it right up. *shrug* 3. Paste + cheese method: This is what we're doing now. I add a VERY small amount of water to make a thick paste, which I form into a ball with my fingers. Then I smash cheese around it so that none (or at least very little) of the MaxxiSAMe ball is showing. If it is showing, he will not touch the stuff - or sometimes will sort of "work" at it to get the cheese off and spit the MaxxiSAMe out. This is why I don't think it would work to mix the paste with something he enjoys: he would still know the MaxxiSAMe is in there. I think this method would work better with lunch meat, but that's not something we normally have around the house, and it goes bad faster than cheese slices. This method would probably work okay with a PillPocket type treat that has a large enough pocket. So, in conclusion, Barney still thinks the stuff is super gross which makes administration a bit of an ordeal, but I have reason to believe it might be helping his CCD so that outweighs any difficulties in giving it to him. I do still wish it came in tablet form; I picture it being like Cosequin, where it's not a coated tablet but more of a compressed powder type tablet that can be broken if needed. Thanks again to the makers of this product for supplying such a high quality product, and for responding to reviews in such a thoughtful, detailed way! ---- UPDATE 6/17/2016: After my last update, the owners of MaxxiSAMe were not content that Barney still wasn't super into the stuff. They actually sent me a free bottle of their MaxxiOmega oil to try mixing that with the MaxxiSAMe, which is super awesome of them. Turns out, it totally worked. I mix his SAMe dosage with about a pump and a half of the oil, smear it on a piece of cheese and wrap the cheese sushi-style, and he gobbles it right up. He still won't QUITE eat it without cheese (though he acts like he MIGHT when I've offered it to him), but I at least don't have to try to smash the cheese all around it to hide every speck of the MaxxiSAMe. Thank you!! ### ⭐⭐⭐⭐⭐ The SAMe is helping and the cognitive benefit is huge (update) *by B***T on December 7, 2016* I previously gave our 10-yr old pointer a chewable SAMe tablet to help control unexplained elevated liver values, but manufacturer changed the formula and our dog would no longer eat it unless buried in food. Since it needed to be given on an empty stomach, that was not ideal. I regularly search for any alternative products--finding nothing much different--and suddenly there was MaxxiSAMe claiming to be fine given with food. Information on the product said it was beneficial for liver health as well as cognitive function. I wasn't looking for the latter, but didn't think it would be in any way a harmful effect. After a brief period of slowly introducing this powder--she didn't care for the flavor, due I assume to the heavy artichoke taste--she began happily eating her food with this supplement in it. It was helpful that she gets some wet food; when it was just dry food the powder would fall to the bottom more readily and got left there. After several weeks we were surprised to notice that she was reverting to more energetic, alert, puppy-like behaviors, and since nothing else had changed we attribute this to improved cognitive function from MaxxiSAMe. I have recommended MaxxiSAMe to my veterinarian who agreed it looks great and seems worthy of trial by other patients. I gave it only 4 stars because the taste was a hurdle for our dog to get over. Also--although I have no reason to blame this product--her liver values have increased a bit, which is not uncommon for her from time to time anyway; but I give her SAMe to manage them so time will tell how they might fluctuate as she stays on this product. As long as they don't spiral out of control, the SAMe is helping, and the cognitive benefit is huge. UPDATE 11/26/17 -- Recently my pointer had her liver values checked again and they were much lower than before! That was the only hold-up in giving this product five stars, so now I can do that and confirm that this product has been great. I have come to trust this company and also have started my dog on their MaxxiFlex joint supplement to help with her arthritis and this is helping her too. ### ⭐⭐⭐⭐⭐ My girl has cancer and it still works wonders! *by M***H on April 22, 2019* My dog, Ginny, has liver cancer. She can still live longer as long as we keep a very close eye on her blood values and diet. I could not afford the expensive Denamarin. I put her on this along with a cheap Milk Thistle supplement and give both twice daily. Within 3 days her coat became more luxurious. It was shiny and silky where before it was dull and dry. I'm going to do a little TMI but her poop went from bright orange to normal and it also helped the GI upset that she had been having, also due to her liver cancer. I mean, I want to stop short of saying that this thing is a "miracle drug" simply because I am a human nurse and there is no such thing. Still, I never would have imagined how well this worked out for her. If I had to say something I don't like it would be the flavor, which needs enhancing. The flavor was not something she cared for. I started mixing it with some yogurt and a very little applesauce. She really likes it with that and the yogurt and applesauce also help the GI upset. My veterinarian was skeptical. She insisted that I buy Denamarin but as I said, I cannot afford it. However, when she saw her liver values after only a month and a half, she was sold. She wants me to bring the container when I finish with it so she can recommend it to others to see if that helps them. This is much cheaper than anything else that I can find on the market, if you find something else, please comment and let me know. I did miss a couple of doses due to emergency circumstances (I broke my hand and had to have surgery) and I will say that within two days she was back to orange poops and her fur changed back to dry and dull. About that same time I figured out how to handle it with my giant cast with pins and such. All in all, I really stand by this stuff. I would say it is probably pretty healthy for dogs without illness but check with your own vet first, of course. You can never be too sure. ## Frequently Bought Together - maxxipaws maxxiSAMe Advanced SAM-e Powder Supplement - Liver, Cognitive & Joint Support for Dogs, 5.3oz - maxxipaws maxxidigest+ Prebiotic & Probiotic for Dogs 13.2oz | Dog Probiotic Powder with Advanced Digestive Enzymes for Gut Health & Immunity | Supports Digestion, Food Sensitivities & Itchy Skin - maxxipaws maxxiomega Omega 3, 6 & 9 Oil Supplement - Skin & Coat Support for Dogs, 10oz --- ## Why Shop on Desertcart? - πŸ›’ **Trusted by 1.3+ Million Shoppers** β€” Serving international shoppers since 2016 - 🌍 **Shop Globally** β€” Access 737+ million products across 21 categories - πŸ’° **No Hidden Fees** β€” All customs, duties, and taxes included in the price - πŸ”„ **15-Day Free Returns** β€” Hassle-free returns (30 days for PRO members) - πŸ”’ **Secure Payments** β€” Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** β€” Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.com.kw/products/18122351-maxxipaws-maxxisame-sam-e-for-dogs-liver-and-cognitive-support](https://www.desertcart.com.kw/products/18122351-maxxipaws-maxxisame-sam-e-for-dogs-liver-and-cognitive-support) --- *Product available on Desertcart Kuwait* *Store origin: KW* *Last updated: 2026-08-28*