---
product_id: 258595779
title: "Doctor's Best SAM-e Mood & Joint Support & Liver Health (Pharmaceutical Grade/Non-GMO/Gluten Free/Vegetarian), Tablet, 60 Count (Pack of 1)"
brand: "doctor's best"
price: "KD 21.46"
currency: KWD
in_stock: true
reviews_count: 6
category: "Doctor's Best"
url: https://www.desertcart.com.kw/products/258595779-doctors-best-sam-e-mood-and-joint-support-and-liver
store_origin: KW
region: Kuwait
---

# Supports joint comfort & mobility Boosts brain neurotransmitters Pharmaceutical grade purity Doctor's Best SAM-e Mood & Joint Support & Liver Health (Pharmaceutical Grade/Non-GMO/Gluten Free/Vegetarian), Tablet, 60 Count (Pack of 1)

**Brand:** doctor's best
**Price:** KD 21.46
**Availability:** ✅ In Stock

## Summary

> ✨ Elevate your mind, move with ease, and detox like a pro 🧬

## Quick Answers

- **What is this?** Doctor's Best SAM-e Mood & Joint Support & Liver Health (Pharmaceutical Grade/Non-GMO/Gluten Free/Vegetarian), Tablet, 60 Count (Pack of 1) by doctor's best
- **How much does it cost?** KD 21.46 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.com.kw](https://www.desertcart.com.kw/products/258595779-doctors-best-sam-e-mood-and-joint-support-and-liver)

## Best For

- doctor's best enthusiasts

## Why This Product

- Trusted doctor's best brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Liver Detox & Health:** Supports natural liver detoxification pathways for sustained vitality and wellness.
- • **Joint Comfort & Mobility:** Scientifically proven to promote joint ease and flexibility, keeping you active and agile.
- • **Mood & Cognitive Clarity:** Clinically backed SAMe enhances dopamine, serotonin & norepinephrine metabolism for sharper focus and elevated mood.
- • **Clean & Conscious Formula:** Non-GMO, gluten-free, vegan, and pharmaceutical grade—because your health deserves premium quality.
- • **Decades of Clinical Validation:** Backed by 18 controlled human trials over 40 years, ensuring trusted, proven effectiveness.

## Overview

Doctor's Best SAM-e is a pharmaceutical-grade, non-GMO, gluten-free, and vegan supplement clinically proven to enhance mood, cognitive function, joint comfort, and liver health. Supported by 18 controlled human trials spanning 40 years, it optimizes neurotransmitter metabolism and promotes overall wellness for the modern professional seeking balanced vitality.

## Description

Doctor’ s Best SAM-e is proven to enhance mood and promote cognitive health. It is essential for the healthy metabolism of the major brain transmitters’ dopamine, serotonin and norepinephrine. In addition, SAM-e promotes joint comfort and mobility and supports liver health and detoxification. SAM-e effectiveness has been published in 18 controlled human trials published over 40 years. Doctor’ s Best SAM-e uses pharmaceutical grade materials. SAM-e is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. SAM-e optimized for potency, stability, and to survive the stomach acid and reach the intestine (where it is absorbed). Effectiveness of SAM-e has been backed by at least 18 controlled human trials published over almost four decades.

Review: Makes me fill very ill - After only a couple of days of taking, these make me feel very ill. They make me go very pale in colour (to the point people are telling me I look pale), and not so Much a headache, but a heavy feeling down one side of my head. I wanted them for Joint support but I will pass…
Review: SAMe was a recommended supplement in Dr. Daniel Amen's book, "Making a Good Brain Great". There is a section in the brain, called the Deep Limbic System (DLS) and when it is not functioning right (excessive activity in this part of the brain), these problems can occur: depression, sadness, focusing on the negative, irritability, low motivation and energy, negativity, social disconnection/isolation, low self-esteem, crying spells, feelings of hopelessness or worthlessness. I was experiencing all of these. Some days I would be fine and other days I felt like I was losing my mind. I had absolutely nothing to be depressed/sad about and the littlest things would bother me and/or make me upset. I was also very irritable. It was getting out of control and it was really affecting my life and my relationship with my boyfriend. I am not too keen on taking any type of pill, which is why I avoided going to see a doctor. I knew he/she would only prescribe me anti-depressants of some sort, which are not only expensive, but also have many negative side effects. This is when I decided to give SAMe a try - and it has changed my life like I never thought possible. It improved my mood and my motivation. I am not nearly as negative and irritable as I was before and I feel really good about my life and in general. For the women out there, I also noticed an improvement in my PMS symptoms. A few things to take note of: -Check with your doctor first before taking. I didn't, but you really should. -Start off with a lower dose. I first started with 400mg and after a few days I started getting anxiety and also a headache shortly after taking. The better dose for me is 200mg, but everyone is different. -Take a vitamin B supplement with SAMe. More specifically, B12, B6 and Folate. This helps with absorbency. -DO NOT take if you have bipolar disorder or are taking other anti-depressants. SAMe is best taken on an empty stomach. Wait 30 minutes or so before eating. I take mine in the morning, along with a vitamin B complex and it has worked out very well. Also be sure to give it time to work. I saw the most improvement after 2 weeks of daily usage. Hope this helps :-)

## Features

- Doctor's Best SAMe is proven to enhance mood and promote cognitive health
- SAMe is essential for the healthy metabolism of the major brain transmitters dopamine, serotonin and norepinephrine
- SAMe has been proven to promote joint comfort and mobility and supports liver health and detoxification
- SAMe's effectiveness has been proven with 18 controlled human trials published over 40 years
- Pharmaceutical grade, Non-GMO, Gluten Free, Vegan

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B002DP1V8A |
| ASIN  | B002DP1V8A |
| Additives | Gluten Free |
| Age Range Description | Adult |
| Allergen Information | Gluten Free, Soy Free |
| Best Sellers Rank | #51,833 in Health ( See Top 100 in Health ) #1,479 in Multivitamins Nutritional Supplements |
| Brand | Doctor's Best |
| Customer Reviews | 4.5 4.5 out of 5 stars (1,267) |
| Customer reviews | 4.5 4.5 out of 5 stars (1,267) |
| Date First Available | 7 August 2012 |
| Format | Tablet |
| Is Discontinued By Manufacturer  | No |
| Item model number  | DRB-00206 |
| Manufacturer  | DOCCA |
| Product Dimensions  | 4.45 x 8.26 x 15.88 cm; 9.07 g |
| Serving Recommendation | 1 tablet twice daily between meals |
| Units | 60 Count |
| Weight | 0.15 Pounds |

## Product Details

- **Brand:** Doctor's Best
- **Diet type:** Vegan
- **Flavour:** Unflavored
- **Item dimensions L x W x H:** 44 x 83 x 159 millimeters
- **Item form:** Tablet
- **Item weight:** 9 g
- **Primary supplement type:** multivitamin
- **Product benefits:** Bone & Joint Health
- **Special ingredients:** Gluten Free
- **Unit count:** 60 Count

## Images

![Doctor's Best SAM-e Mood & Joint Support & Liver Health (Pharmaceutical Grade/Non-GMO/Gluten Free/Vegetarian), Tablet, 60 Count (Pack of 1) - Image 1](https://m.media-amazon.com/images/I/51Kjov1uE4L.jpg)

## Customer Reviews

### ⭐ Makes me fill very ill
*by J***G on 4 December 2022*

After only a couple of days of taking, these make me feel very ill. They make me go very pale in colour (to the point people are telling me I look pale), and not so Much a headache, but a heavy feeling down one side of my head. I wanted them for Joint support but I will pass…

### ⭐⭐⭐⭐⭐ Review
*by E***N on 13 September 2012*

SAMe was a recommended supplement in Dr. Daniel Amen's book, "Making a Good Brain Great". There is a section in the brain, called the Deep Limbic System (DLS) and when it is not functioning right (excessive activity in this part of the brain), these problems can occur: depression, sadness, focusing on the negative, irritability, low motivation and energy, negativity, social disconnection/isolation, low self-esteem, crying spells, feelings of hopelessness or worthlessness. I was experiencing all of these. Some days I would be fine and other days I felt like I was losing my mind. I had absolutely nothing to be depressed/sad about and the littlest things would bother me and/or make me upset. I was also very irritable. It was getting out of control and it was really affecting my life and my relationship with my boyfriend. I am not too keen on taking any type of pill, which is why I avoided going to see a doctor. I knew he/she would only prescribe me anti-depressants of some sort, which are not only expensive, but also have many negative side effects. This is when I decided to give SAMe a try - and it has changed my life like I never thought possible. It improved my mood and my motivation. I am not nearly as negative and irritable as I was before and I feel really good about my life and in general. For the women out there, I also noticed an improvement in my PMS symptoms. A few things to take note of: -Check with your doctor first before taking. I didn't, but you really should. -Start off with a lower dose. I first started with 400mg and after a few days I started getting anxiety and also a headache shortly after taking. The better dose for me is 200mg, but everyone is different. -Take a vitamin B supplement with SAMe. More specifically, B12, B6 and Folate. This helps with absorbency. -DO NOT take if you have bipolar disorder or are taking other anti-depressants. SAMe is best taken on an empty stomach. Wait 30 minutes or so before eating. I take mine in the morning, along with a vitamin B complex and it has worked out very well. Also be sure to give it time to work. I saw the most improvement after 2 weeks of daily usage. Hope this helps :-)

### ⭐⭐⭐⭐⭐ Review
*by S***A on 3 November 2018*

I’ve suffered from depression since I was 11. I am now 34. I was prescribed an Antidepressant in my twenties and I didn’t like the effect it had on me. I’ve always fought this on my own and tried different methods but I could not stay consistent due to my frequent breakdowns and mood changes. My coworker show this to me and I went ahead and gave it a try and I absolutely love it. I can’t explain the change in my moods, it’s like I’m more clear and can enjoy being happy longer with simple things. My thoughts aren’t spiraling out of control..I can control my emotions more . I am able to get things done instead of finding a way to lay in bed or distant myself. It’s truly amazing. I’m telling more people about this. It truly has made a difference in my life and others. The only down side to this is it does cause diarrhea lol but honestly I’d take diarrhea over depression any day. I’m now just looking into a probiotic lol ***also it’s not just the supplement that going to change you, basically it has stabilized me to where I can do things to better myself and strengthen myself mentally. If you are taking this for depression you can’t just depend on a pill you have to go out and take action. Utilize it to tackle your challenges goals and new positive habits. I hope It does good to you how it has done for me. <3

## Frequently Bought Together

- Doctor's Best SAM-e Mood & Joint Support & Liver Health (Pharmaceutical Grade/Non-GMO/Gluten Free/Vegetarian), Tablet, 60 Count (Pack of 1)
- Doctor's Best SAM-e 400 mg, Vegan, Gluten Free, Soy Free, Mood and Joint Support, 60 Enteric Coated Tablets
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*Product available on Desertcart Kuwait*
*Store origin: KW*
*Last updated: 2026-03-04*