---
product_id: 43039649
title: "extreme V Azendus SAM-e Mood Support 400mg, 60 Count, Same Butanedisulfonate Fiber Enteric Coated Tablets"
brand: "extreme v"
price: "KD 9.90"
currency: KWD
in_stock: false
reviews_count: 8
url: https://www.desertcart.com.kw/products/43039649-extreme-v-azendus-sam-e-mood-support-400mg-60-count
store_origin: KW
region: Kuwait
---

# 400mg potent SAMe dose Individually foil-sealed for freshness Enteric coated for max bioavailability extreme V Azendus SAM-e Mood Support 400mg, 60 Count, Same Butanedisulfonate Fiber Enteric Coated Tablets

**Brand:** extreme v
**Price:** KD 9.90
**Availability:** ❌ Out of Stock

## Summary

> 💡 Elevate your mood naturally — because your brain deserves premium care.

## Quick Answers

- **What is this?** extreme V Azendus SAM-e Mood Support 400mg, 60 Count, Same Butanedisulfonate Fiber Enteric Coated Tablets by extreme v
- **How much does it cost?** KD 9.90 with free shipping
- **Is it available?** Currently out of stock
- **Where can I buy it?** [www.desertcart.com.kw](https://www.desertcart.com.kw/products/43039649-extreme-v-azendus-sam-e-mood-support-400mg-60-count)

## Best For

- extreme v enthusiasts

## Why This Product

- Trusted extreme v brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Advanced Enteric Coating:** Protects SAMe from stomach acid, ensuring maximum absorption where it counts.
- • **Freshness-Sealed Foil Packs:** Each tablet is individually wrapped to preserve stability and potency until the last dose.
- • **Clinically Potent 400mg Dose:** Delivers a powerful, plant-based SAMe boost to support mood and neurotransmitter synthesis.
- • **Trusted Brand with Responsive Service:** Azendus’ commitment to quality and customer care means you never run out of your mood support.
- • **Natural Mood Support Without Side Effects:** Helps regulate serotonin, dopamine, and norepinephrine without weight gain or sexual dysfunction.

## Overview

Extreme V Azendus SAM-e Mood Support offers a potent 400mg dose of natural SAMe-Butanedisulfonate in enteric-coated, foil-sealed tablets designed for superior bioavailability and stability. This plant-based supplement supports neurotransmitter production critical for mood regulation without common side effects like weight gain or sexual dysfunction. Trusted by users for its effectiveness and backed by responsive customer service, it’s a premium choice for professionals seeking natural, reliable mood enhancement.

## Description

Buy extreme V Azendus SAM-e Mood Support 400mg, 60 Count, Same Butanedisulfonate Fiber Enteric Coated Tablets on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: How SAMe compares to longtime antidepressants - Taking 2 of the 400mg dose each morning for anxiety/depression (in other countries where SAM-e can be prescribed for such problems, 800mg is the standard MINIMUM dose and lower doses are usually ineffective). I’ve been on antidepressants of all different brands/kinds for 10 years now and they all have heavy side effects. Ultimately being emotionally blunted and losing any sense of motivation to do things I had to or even wanted to is what made me decide I had enough. However the nature of my particular problems are too serious to leave unchecked, so I started using this as soon as I worked down and got off the antidepressant, working up from the smallest dose over a month or two (be sure you’re off serotonin-altering medications like SSRIs or SNRIs before you start). Note that it will likely take a month or more to kick in, just like serotonin-altering medications. I chose this brand because it came up in research as one of the better brands you can get in the U.S., as it uses butanedisulfonate instead of the poorer quality tosylate that more commonly seen brands use (which were the ones I was familiar with from past dabbling at 200mg doses). I wish it wasn’t so costly but alas. Know that the 400mg pill is bigger than the 200mg one, multivitamin size. Unfortunately the 200 and 400mg boxes have no difference in box branding so make sure you’re getting the right dose and number of pills. I still have to take a different, non-antidepressant medication for a couple of the anxiety/sleep disorders, but the SAM-e has definitely taken the sharp edge off my anxiety and kept major depression away even through a very distressing life change, and without any noticeable side effects. It gives you enough help to keep you sane but doesn’t zombify you, letting you feel emotions (even if that can be hard at times) and learn coping strategies and healthy management of your disorders so that they can’t run your life anymore. Instead of being crutches like antidepressants, SAM-e is a handrail. You have to stand on your own two feet but you still have help so you don’t fall. Drugs are certainly stronger, but at more personal cost. What makes me like Azendus specifically is that when they accidentally sent me the wrong dosage and count days before I was about to run out they immediately got back to my return request (within an hour), refunded me, and sent me more with priority shipping at no cost to me. They were low on stock with the specific dose/count I typically get so they sent me enough of the 30 count to match up to my usual 60 count. I was very relieved and impressed by that and will definitely continue using this brand despite the lack of Prime shipping because I trust that honesty and reliability and that’s something you need if you’re using SAM-e as consistently as you would a prescription drug. Definitely recommend!
Review: Focus - I started taking these for focus and mood. The difference is subtle but allows me to stay focused when my typical afternoon slump hits. Before was fighting to get things done in the afternoons, now it takes a moderate amount of effort even when I feel tired. I also feel more motivated on the weekends. Instead of staring at my to-do list and maybe getting one thing checked off, I can get through a reasonable number without losing steam. No stomach or other side effects.

## Features

- SAMe-Butanedisulfonate is a natural metabolite that participates in over 100 essential biochemical reactions in the cells of all animals. SAMe donates molecules to help manufacture the neurotransmitters (serotonin, norepinephrine, dopamine) involved in mood regulation as well as other necessary metabolites. So, rather than artificially altering the way that neurotransmitters are released or taken up by neurons, SAMe helps the body build more neurotransmitter molecules.
- SAMe oxidizes rapidly when exposed to air, so, in order to maintain potency, SAMe tablets must be manufactured very carefully, enterically coated, and preserved in individual foil blister packs. Those who have tried Azendus-Butanedisulfonate have seen a noticeable difference to other generic SAMe-Tosylate form.
- SAMe-Butanedisulfonate does not cause any weight gain or sexual dysfunction.
- Azendus customers have been able to reduced daily dosages, when compared to other generic SAMe due to Azendus-Butanedisulfonate potency and bioavailability. Adjust your daily dosage intake, as required.
- 400mg (S-Adendosylmethionine Butanedisulfonate) Plant Based Enteric Coated Tablets No plasticizers, synthetic co-polymers or artificial colors Gentle Stomach Formula - NATURAL SAMe Stable & Bioavailable Butanedisulfonate Form

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B01GK1YP7Q |
| Best Sellers Rank | #226,828 in Health & Household ( See Top 100 in Health & Household ) #10,879 in Blended Vitamin & Mineral Supplements |
| Customer Reviews | 4.4 4.4 out of 5 stars (198) |
| Date First Available  | June 3, 2016 |
| Is Discontinued By Manufacturer  | No |
| Manufacturer  | extreme V |

## Product Details

- **Brand:** extreme V
- **Dosage Form:** Tablet
- **Flavor:** Unflavored
- **Item Form:** Tablet
- **Material Feature:** Plant Based
- **Number of Items:** 1
- **Product Benefits:** Brain Health Support
- **Servings per Container:** 60
- **Special Ingredients:** Coenzyme Q
- **Unit Count:** 60 Count

## Images

![extreme V Azendus SAM-e Mood Support 400mg, 60 Count, Same Butanedisulfonate Fiber Enteric Coated Tablets - Image 1](https://m.media-amazon.com/images/I/81FMG4y1jTL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ How SAMe compares to longtime antidepressants
*by M***P on March 2, 2020*

Taking 2 of the 400mg dose each morning for anxiety/depression (in other countries where SAM-e can be prescribed for such problems, 800mg is the standard MINIMUM dose and lower doses are usually ineffective). I’ve been on antidepressants of all different brands/kinds for 10 years now and they all have heavy side effects. Ultimately being emotionally blunted and losing any sense of motivation to do things I had to or even wanted to is what made me decide I had enough. However the nature of my particular problems are too serious to leave unchecked, so I started using this as soon as I worked down and got off the antidepressant, working up from the smallest dose over a month or two (be sure you’re off serotonin-altering medications like SSRIs or SNRIs before you start). Note that it will likely take a month or more to kick in, just like serotonin-altering medications. I chose this brand because it came up in research as one of the better brands you can get in the U.S., as it uses butanedisulfonate instead of the poorer quality tosylate that more commonly seen brands use (which were the ones I was familiar with from past dabbling at 200mg doses). I wish it wasn’t so costly but alas. Know that the 400mg pill is bigger than the 200mg one, multivitamin size. Unfortunately the 200 and 400mg boxes have no difference in box branding so make sure you’re getting the right dose and number of pills. I still have to take a different, non-antidepressant medication for a couple of the anxiety/sleep disorders, but the SAM-e has definitely taken the sharp edge off my anxiety and kept major depression away even through a very distressing life change, and without any noticeable side effects. It gives you enough help to keep you sane but doesn’t zombify you, letting you feel emotions (even if that can be hard at times) and learn coping strategies and healthy management of your disorders so that they can’t run your life anymore. Instead of being crutches like antidepressants, SAM-e is a handrail. You have to stand on your own two feet but you still have help so you don’t fall. Drugs are certainly stronger, but at more personal cost. What makes me like Azendus specifically is that when they accidentally sent me the wrong dosage and count days before I was about to run out they immediately got back to my return request (within an hour), refunded me, and sent me more with priority shipping at no cost to me. They were low on stock with the specific dose/count I typically get so they sent me enough of the 30 count to match up to my usual 60 count. I was very relieved and impressed by that and will definitely continue using this brand despite the lack of Prime shipping because I trust that honesty and reliability and that’s something you need if you’re using SAM-e as consistently as you would a prescription drug. Definitely recommend!

### ⭐⭐⭐⭐⭐ Focus
*by M***M on April 15, 2024*

I started taking these for focus and mood. The difference is subtle but allows me to stay focused when my typical afternoon slump hits. Before was fighting to get things done in the afternoons, now it takes a moderate amount of effort even when I feel tired. I also feel more motivated on the weekends. Instead of staring at my to-do list and maybe getting one thing checked off, I can get through a reasonable number without losing steam. No stomach or other side effects.

### ⭐⭐⭐⭐⭐ Measurably better anti-depressant effect than regular SAMe!
*by S***T on January 30, 2019*

Very pleased with the effectiveness of this formulation of SAMe! I have used other brands of SAMe for over 15 years to successfully manage moderate (but constant) depression and anxiety symptoms. Decided to try Azendus after I read that the form they manufacture has been shown more effective in research than the Tosylate form. Within a week I noticed a lift in mood and affect, after a month of feeling 25% more positive and clearly less anxious than the last 2 years, with no changes in external situations, I now know this form works much better for me! For those of us that manage to live with chronic depression, this is a breakthrough. Of course I also eat a healthy diet, exercise, make proper rest and sleep a priority, meditate and work on my responses to external triggers, but even with all that in place for years, this form of SAMe has made that extra, measurable difference between merely coping to actually feeling lighter-hearted! Very grateful to have found this.

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*Product available on Desertcart Kuwait*
*Store origin: KW*
*Last updated: 2026-01-25*