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💋 Smooth lips, sharper looks — because your smile deserves the spotlight!
Dermelect Smooth Upper Lip & Perioral Anti-Aging Treatment is a professional-strength 15ml cream designed to visibly reduce fine lines and vertical lip wrinkles. Featuring a potent blend of hyaluronic filling spheres, retinol, and Matrixyl 3000, it hydrates, firms, and primes lips for flawless lipstick application. Dermatologist-tested and free from gluten, parabens, and oils, it offers precise application via a unique ceramic tip, making it a must-have for millennial professionals seeking youthful, polished lips.












| ASIN | B00EOQRCGG |
| Additional Features | Anti-aging treatment and lipstick primer in one |
| Best Sellers Rank | #21,191 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #2 in Lipstick Primers |
| Brand | Dermelect |
| Brand Name | Dermelect |
| Color | White |
| Customer Reviews | 3.9 out of 5 stars 1,392 Reviews |
| Finish Type | Dermelect Smooth Upper Lip & Perioral Anti-Aging Treatment - Professional Strength 15ml |
| Is the Item Heat Sensitive? | No |
| Item Form | Cream |
| Item Weight | 0.5 Ounces |
| Manufacturer | Dermelect Cosmeceuticals |
| Manufacturer Part Number | 1006 |
| Material Type Free | Gluten Free, Paraben Free, oil free |
| Model Number | 177472 |
| Number of Items | 1 |
| Product Benefits | Specially developed to address the look of discoloration, vertical lip lines, and smile lines surrounding the mouth while doubling as a lipstick primer to enhance lipstick application and longevity. Product Benefits Specially developed to address the look of discoloration, vertical lip lines, and smile lines surrounding the mouth while doubling as a lipstick primer to enhance lipstick application and longevity. See more |
| Skin Type | All |
| Special Ingredients | Retinol, Matrixyl 3000 |
| UPC | 855702001066 |
T**G
This Actually Treats Lip Lines — Not a Glossy Gimmick, a Real Treatment
At 52, post-menopausal, with dry, mature skin, the area around the mouth has become one of the places I pay the closest attention to. Fine lines around the lips can be stubborn, and they often need a different approach than the rest of the face. Many products marketed for this area are really just trendy lip glosses or temporary plumpers making unrealistic promises. This is very different. This is not an instant plumper. It is not a shiny lip product pretending to erase wrinkles in ten minutes. This is a treatment product, and in my experience, it actually works. The first thing that is important to understand is how to use it. This is not something you apply on the lips themselves like a balm or gloss. It is meant for the skin around the lips and along the lip line—the area where vertical lines, texture, and loss of smoothness tend to show up over time. That distinction matters, and I think some people may misunderstand the product if they expect it to function like a lip treatment. The texture is smooth, comfortable, and easy to apply precisely around the mouth. It absorbs nicely and does not feel greasy or messy. I like using it as part of my skincare routine rather than as a cosmetic product. What I appreciate most is that it takes the long-game approach. This is not going to remove years of lip lines overnight, and no honest topical product can truly promise that. What it can do is help soften the appearance of lines, improve smoothness, and make the lip area look better with consistent use. That has been my experience. Over time, the skin around my lips looked smoother, a little firmer, and better maintained. Fine lines appeared softened rather than sharply etched, especially when I stayed consistent with use. For mature skin, that kind of gradual improvement is often much more valuable than a flashy temporary effect that disappears in an hour. I also like that it focuses on a commonly neglected area. Many people treat the face but forget the mouth area entirely, even though it often shows aging quickly. Who I think this is great for: mature skin, smokers’ lines or vertical lip lines, dryness around the mouth, people wanting a true treatment product, and anyone looking for gradual improvement rather than hype. Who may want to skip it: anyone wanting an instant plumping gloss effect, younger users without concerns in this area, or people expecting dramatic overnight wrinkle removal. Value-wise, I think it earns its place because there are not many products specifically focused on this concern that are actually treatment-oriented. Used consistently, this is one of the better products I’ve found for the lip line area.
T**A
Smoother, Softer Lip Area After Just a Few Uses
⭐⭐⭐⭐⭐ I’ve only been using the Dermelect Smooth Upper Lip & Perioral Anti-Aging Treatment for a short time, but I’m already impressed with how smooth and hydrated my upper lip area feels. The formula absorbs quickly, layers well under makeup, and doesn’t feel sticky or heavy. I love that it specifically targets the delicate lip and smile line area because that’s something I’ve been trying to focus on more in my skincare routine. The packaging feels luxe and a little goes a long way. Excited to keep using it and see even more results over time!
K**N
Innovative anti-aging product
Dermelect Anti-Aging Smooth Upper Lip & Perioral Treatment is innovative and has quickly earned a spot in my routine. The sleek 15ml tube looks and feels professional strength. I have been using this product for a week now. I apply before my makeup in the morning and then in the evening before bed. The ceramic applicator allows easy application. The texture is lightweight yet powerful, leaving the skin around my mouth feeling nourished and plumped. I do not apply directly on my lips. Formulated with hyaluronic filling spheres, retinol and Matrixyl 3000, it hydrates, smooths and works well to soften the pesky, fine lines around my mouth. In just a week, I’ve noticed the fine lines near my upper lip looking less noticeable. I am hopeful that my smile creases will also soften with longer term use. Additionally, I appreciate that this product is gluten-free, paraben-free and oil-free, making it feel clean and trustworthy. Knowing that it’s dermatologist-tested is reassuring as well. This Anti-Aging Smooth Upper Lip & Perioral Treatment has become an essential part of my anti-aging skincare and self-care routine.
L**S
Does not act as fast as I want
I have used for as long as I need to see results.
A**S
I want my money back
Guarantee or money back I want my money back Used it all not one line or wrinkle faded Does NOT WORK
G**S
Upper lip treatment
With DERMELECT I have seen an incredible improvement in my expression lines and my upper lip is incredible how can you have results in just one week 😍
M**R
Unhappy
I have not noticed any difference. Have been using it for several weeks twice a day. Very disappointed was hoping this was going to work. I’ve tried a number of things. Did not want to do injectables.
S**Y
It is a little pricey so occasional sales for this product would be helpful.
Works amazingly on areas of my face!
J**S
Amazing
Absolutely love this product, I am a smoker and have quite deep lines above my top lip. I have been using only a couple of days but it does actually make them less noticeable. Can’t wait to see what they look like in a month. Tried so many products in the past from every price range. This is the only one I can honestly say is making a difference.
A**.
It works for a while
It’s good
A**R
Didn’t work for me
It made no difference to my lines at all. I wanted it to work and applied twice daily till the tube ran out, took before photos so I could check. Disappointed but not 😳
L**R
Burning sensation in gums
Burns gums
K**R
Waste of money
Made no difference whatsoever
Trustpilot
2 weeks ago
4 days ago