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🐾 Calm, Balance & Shine — Because your dog deserves the best!
PranaPets Lignans & Melatonin with Biotin Blend is a scientifically formulated supplement designed for dogs over 25 lbs suffering from Cushing’s disease. It combines 80mg of SDG lignans from flaxseed extract, 6mg of melatonin, and 3mg of biotin per serving to naturally support adrenal health, promote restful sleep, and enhance skin and coat condition. Free from artificial additives and allergens, this non-GMO, gluten- and soy-free formula offers a clean, effective way to improve your dog’s overall well-being and manage Cushing’s symptoms with trusted, vet-approved ingredients.


















| ASIN | B0DFJCL5BG |
| Active Ingredients | Active Ingredients per 2 tablets: SDG Lignans (from Flaxseed Extract)…80 mg, Melatonin…6 mg, Biotin…3 mg Active Ingredients Active Ingredients per 2 tablets: SDG Lignans (from Flaxseed Extract)…80 mg, Melatonin…6 mg, Biotin…3 mg See more |
| Allergen Information | Non-GMO |
| Best Sellers Rank | #6,909 in Pet Supplies ( See Top 100 in Pet Supplies ) #31 in Dog Herbal Supplements |
| Brand | PranaPets |
| Brand Name | PranaPets |
| Customer Reviews | 4.5 out of 5 stars 75 Reviews |
| Flavor | Beef |
| Included Components | Tablets |
| Item Type Name | Better Sleep, Calming |
| Manufacturer | PranaPets |
| Manufacturer Part Number | PPMELLIG2-BIO |
| Model Number | PPMELLIG2-BIO |
| Product Benefits | Anti-Hairfall, Cushing's relief for dogs, Immune Support, Skin Care |
| Specific Uses For Product | Active |
| UPC | 850067825012 |
| Unit Count | 1.0 Count |
| Warranty Description | 366 |
S**E
Save Your Baby — We Did!
I am not kidding, this product changed my dog within the first two days of taking it. A little backstory on our baby. She is a boxer-pit mix, super sweet baby who is currently 12 years old. We have been super worried about her because she started to went the bed, wet herself when on the couch, etc. I tested her blood sugars (all normal), thought it was a UTI—vet tested her, no uti. Thought it might be a bladder stone, no stones. So I thought of Cushing and our vet said “you know you might be right.” But he couldn’t recommend anything for her to take because the normal medication that he typically prescribed is no longer being manufactured. So I started to do some research and found out how impactful melatonin can be in a dog’s system if they suffer from Cushing’s. Literally I could not purchase this product any faster. It got to my house the next morning. I gave our baby her first dose, and guys, seriously, by that afternoon she was already not looking for water to over drink. She slept peacefully (which has been an issue for her lately because she’s so water driven from the disease), so I am so happy to report that if you are thinking twice, please don’t. This has been a life changer for our little girl, and I hope other people find it just as useful!
K**A
Works well for senior dogs
This stuff is amazing! My senior dog has been on it for several months and it has MAJORLY helped with her “sun downers”, she is in general less spooked at night. She is on no other medications, just this.
D**T
I 100% believe this supplement saved my Boston Terrier
We were flirting with a Cushing diagnosis about six months ago, but were unable to confirm with certainty. A friend asked Dr. Google and sent me a link to this product. If you’re familiar with adrenal Cushings and traditional diagnosis and treatment, it’s time consuming and EXPENSIVE. I think had we gone with Vetoryl, she’d still be going in for semi-regular labs (all day, fasting, couple hundred bucks a pop) to get dosage right. I didn’t feel I had much to lose, started her on one pill daily, and noticed a difference in less than a week. Proof came with her checkup this fall, in less than 6 months her ALP went from 1622 in April to 470! Our vet was amazed. One note: at first, she would not eat it solo and it’s too big to hide in food. I bought a cheap pill crusher and used that for a while. Now, I just toss a pill into her bowl of kibble and she eats it fine.
B**H
Really helped calm my doggy and let her get rest
My little doggie was diagnosed with Cushing disease. In the evenings especially she was miserable. This medicine helped to calm her and let her rest. I still ended up putting her on vet prescribed medicine, but this really helped us get thru that period before testing to get her on meds. I was hoping it and the other homeopathic meds we tried would work, but after a couple of months it didn’t seem to be enough. I will still use and recommend this product as it really did help settle her down. On nights when she needs a little extra help, I still give her some.
S**E
Parma peta allergy bites
Good supplement
M**Y
Vet recommended - proven results
Our veterinarian recommended this specifically for the lignans for our dog, the other ingredients are a nice bonus. After several months, bloodwork was back to normal. They are chewable, but she does not like the taste, so we bury them in her food. They are pricey, but they work.
H**X
It’s helping reduce symptoms
This definitely reduces the symptoms that my dog has with drinking insane amounts of water and demanding food all day. If I miss her dose for a day or so the symptoms return full throttle.
P**E
Effective
Seems to work great
Trustpilot
1 week ago
2 months ago